Acute kidney injury after prolonged neurosurgical operations

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Abstract

Background
Acute kidney injury (AKI) is a serious condition that causes significant morbidity and mortality in medical and surgical intensive care units. In this environment, the prevalence, risk factors, and prognostic effects of this harmful disorder are well known. But there is paucity about this issue among patients with neurosurgeries. So, this work tried to detect different risk factors for the development of AKI among patients underwent prolonged neurosurgeries.
Methods
Over a two-year duration, 100 patients were recruited in the current study. Those patients were eligible for different neurosurgeries. Baseline data including demographic and laboratory in addition to perioperative data were gathered. The main end point was the development of AKI based on the Kidney Disease Improving Global Outcomes criteria
Results
Fifteen (15%) patients developed AKI; 13 (86.7%) patients had stage I; and 2 (13.3%) patients had stage II AKI. It was found that risk factors for the development of AKI were old age, operative blood loss, and operative transfusion of mannitol. Only two patients were died, and both of them developed AKI.
Conclusion
AKI is a serious complication in patients underwent prolonged neurosurgeries. It has a great effect on patient’s prognosis. Early detection of different risk factors for AKI may help in new lines of therapy for those patients with subsequent improvement in their outcome.

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Egyptian Journal of Anaesthesia
Volume 37, Issue 1
January 2021
Pages 440-444

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